Frontier Computing

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About Frontier Computing

YC company profile

Frontier grows scalable biological brains as an ML training substrate

Frontier is first to grow biological brains at scale, serving biological neural nets with substrate-level colocation of memory and compute, enabling highly cost effective training of large parameter count models.

While academia has traditionally been limited to ~1M neurons in vitro, Frontier has built a pathway to scale to 100M+ neurons by circumventing traditional scaling challenges in biological culture, demonstrating this strategy's functionality by training a biological brain using this scaling primitive to play Frogger.

Frontier is now growing exascale compute clusters to produce substrates capable of long-horizon language reasoning while operating at much higher sample efficiencies than traditional architectures, and collocating memory with compute to enable significantly larger parameter counts than would be tractable for training within traditional compute clusters.

  • YC batch: Summer 2026
  • Founded: 2025
  • Team size: 3
  • Location: London, United Kingdom
  • Country: GB
  • Status: Active
  • Industry: Industrials
  • Stage: Early
  • Tags: Hard Tech, Hardware, AI
  • YC partner: Harshita Arora

Founders

Michael Domarkas — Founder/CEO

19 y/o growing exascale brains for continual learning

prev growing brains in my bedroom

LinkedIn · X

Source: Y Combinator · Retrieved 2026-11-02. Company information is self-reported on YC.